Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM, 10-fold more selective for Flt3 than KIT, PDGFRalpha, PDGFRbeta, RET, and CSF-1R. Phase 1/2.
Molecular Weight:
560.673
CAS Number:
[950769-58-1]
Formula:
C29H32N6O4S
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