S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, > 130-fold selectivity for JAK1/2 versus JAK3. Phase 3.
Molecular Weight:
306.37
CAS Number:
[941685-37-6]
Formula:
C17H18N6
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