A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the Tyrosinase-Related Protein-1 antibody.
Conjugation:
Unconjugated
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence sugge