Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC50 of 2 nM again
Molecular Weight:
429.9
Purity:
95% (HPLC)
CAS Number:
[183319-69-9]
Formula:
C22H23N3O4 . HCl
Target:
EGFR
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