PF-562,271 is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 catalytic activity with a IC50 of 1.5 and 14 nmol/l, respectively (PMID 18339875). In addition, PF-562,271 displayed robust inhibition in an inducible cell-based assay measurin
Molecular Weight:
507.5
Purity:
95% (HPLC)
CAS Number:
[717907-75-0]
Formula:
C21H20F3N7O3S
Target:
FAK, Pyk2
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