BMS-5 is a potent inhibitor of the LIM kinase. It has IC50 values of 7nM and 8 nM for LIMK1 and LIMK2 respectively. LIMK1/2 activity was measured via TCA precipitation assay using a biotinylated ADF (actin depolymization factor) as the protein substrate
Molecular Weight:
431.3
Purity:
98% (HPLC)
CAS Number:
[1338247-35-0]
Formula:
C17H14Cl2F2N4OS
Target:
LIMK1, LIMK2
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