Ponatinib

Product Overview

• Article Name: Ponatinib
• Biozol Catalog Number: ENZ-ENZ-CHM179-0010
• Supplier Catalog Number: ENZ-CHM179-0010
• Alternative Catalog Number: ENZ-ENZ-CHM179-0010-10
• Manufacturer: Enzo Life Sciences
• Category: Sonstiges
• Alternative Names: AP 24534, 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide

Product Description

Ponatinib is a potent multi-target inhibitor of Abl, PDGFRalpha, VEGFR2, FGFR1 and Src with IC50 values of 0.37, 1.1, 1.5, 2.2 and 5.4 nM respectively.

Product Properties

• Molecular Weight: 532.6
• Purity: 98% (HPLC)
• CAS Number: [943319-70-8]
• Formula: C29H27F3N6O
• Target: Abl, PDGF receptor alpha, VEGFR-2, FGFR1, Src Kinase