Selumetinib (AZD6244) is a second-generation, orally available, potent and selective ATP non-competitive inhibitor of MEK 1/2. In direct assays, AZD6244 selectively inhibits purified active MEK1 and MEK2 with an IC50 of 14 nM, and AZD6244 has reported IC
Molecular Weight:
457.7
Purity:
95% (HPLC)
CAS Number:
[606143-52-6]
Formula:
C17H15BrClFN4O3
Target:
MEK-1, MEK-2
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