Momelotinib

Product Overview

• Article Name: Momelotinib
• Biozol Catalog Number: ENZ-ENZ-CHM197-0005
• Supplier Catalog Number: ENZ-CHM197-0005
• Alternative Catalog Number: ENZ-ENZ-CHM197-0005-5
• Manufacturer: Enzo Life Sciences
• Category: Sonstiges
• Alternative Names: CYT 387, N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzamide

Product Description

Using ATP kinase assays, the IC50 values for CYT387 are a follows - JAK1 (11nM), JAK2, (18nM), JAK2 V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC50 < 100nM) detected against CDK2/cyclin A

Product Properties

• Molecular Weight: 414.5
• Purity: 97% (HPLC)
• CAS Number: [1056634-68-4]
• Formula: C23H22N6O2
• Target: JAK1, JAK2, JAK3, JAK2 V617F, TYK2, CDK2, JNK1, PKD3, PKD1, ROCK2, TANK-binding kinase 1