Baricitinib is a selective JAK1 and JAK2 inhibitor. IC50 values are 5.9nm for JAK1, and 5.7nM for JAK2. In cell based assays Baricitinib/INCB-28050 demonstrated inhibition of intracellular signaling of multiple pro-inflammatory cytokines including IL-6 a
Molecular Weight:
469.4
Purity:
99% (HPLC)
CAS Number:
[1187595-84-1]
Formula:
C16H17N7O2S . H3PO4
Target:
JAK1, JAK2
* VAT and and shipping costs not included. Errors and price changes excepted