A1874 is a nutlin-based PROTAC targeting on BRD4, consist of a BRD4-ligand JQ1 linked to a MDM2 E3 ligase ligand RG7388. A1874 possesses dual function as it dose-dependently degraded its target BRD4, accompanied with the downregulation of c-MYC, as well
Molecular Weight:
1173.6
Purity:
98%
CAS Number:
[2064292-12-0]
Formula:
C58H62Cl3F2N9O7S
Target:
BRD4
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