CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18), expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[MEM-170]
Isotype:
Mouse IgG1
Buffer:
Phosphate buffered saline (PBS), pH 7.4
Storage:
2°C to 8°C
Target:
CD11b
Antibody Type:
Monoclonal Antibody
Application Notes:
Functional application: The antibody MEM-170 blocks (not completely) Mac-1-mediated neutrophil binding to fibrinogen. Flow cytometry: Recommended dilution: 1 µg/ml.
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