Bacterially produced recombinant intracellular fragment of human SIT.
SIT (SHP2-interacting transmembrane adaptor protein) is expressed exclusively in lymphoid organs and acts either as a positive or as a negative regulatory element in T cell activation and in T cell development. Binding to Grb2 plays a pivotal role in sig
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[SIT-01]
Isotype:
IgG1
Buffer:
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage:
2°C to 8°C
Antibody Type:
Monoclonal Antibody
Application Notes:
Flow cytometry: Intracellular staining. Western blotting: SIT migrates as an approximately 40 kDa protein that is reduced to approximately 20 kDa by endoglycosidase treatment.
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