HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and human beta2-microglobulin.
Human leukocyte antigen G (HLA-G), belonging to MHC class I glycoproteins, plays important roles in both physiological and pathological immunotolerance. It gives an inhibitory signal to cytotoxic T cells, NK cells, monocytes, and some other immune cells.
Clonality:
Monoclonal
Concentration:
1 mg/ml
Clone Designation:
[87G]
Isotype:
Mouse IgG2a
Buffer:
Phosphate buffered saline (PBS), pH 7.4
Storage:
2°C to 8°C
Target:
HLA-G
Antibody Type:
Monoclonal Antibody
Application Notes:
Flow cytometry: Extracellular and intracellular staining, recommended dilution: 2 µg/ml, positive control: JEG-3 human choriocarcinoma epithelial cell line. Immunohistochemistry (frozen sections): Recommended dilution: 10 µg/ml, incubation: 20 min at 25
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