98% by TLC [50% ethyl acetate in hexanes, Rf = 0.17] NMR conforms
Form:
Off-white solid
CAS Number:
[516480-79-8]
Formula:
C20H14ClN3O2
Application Notes:
Potent selective inhibitor of Chk2 (IC50 = 15 nM). BML-277 has been screened against a panel of 35 kinases, and shows less that 25% inhibition of any other kinase at 10 µM, demonstrating the selectivity1. Also displays radioprotective activity, preventin
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