GW-5074, CAS [[220904-83-6]]

Product Overview

• Article Name: GW-5074, CAS [[220904-83-6]]
• Biozol Catalog Number: FBM-10-1031
• Supplier Catalog Number: 10-1031
• Alternative Catalog Number: FBM-10-1031-5MG,FBM-10-1031-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

c-Raf1 inhibitor

Product Properties

• Molecular Weight: 520.95
• Purity: 98% by TLC NMR conforms
• Form: Dark orange solid MP = 267-268C
• CAS Number: [220904-83-6]
• Formula: C15H8Br2INO2

Application Notes

• Application Notes: Potent inhibitor of cRAF1 kinase (IC50 = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects In vivo via a mechanism that is independent of MEK, ERK, and Akt signa