ZM-447439, CAS [[331771-20-1]]

Product Overview

• Article Name: ZM-447439, CAS [[331771-20-1]]
• Biozol Catalog Number: FBM-10-1037
• Supplier Catalog Number: 10-1037
• Alternative Catalog Number: FBM-10-1037-5MG,FBM-10-1037-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Aurora B kinase inhibitor

Product Properties

• Molecular Weight: 513.59
• Purity: 98% by TLC [10% methanol in methylene chloride, Rf = 0.30]
• Form: White solid
• CAS Number: [331771-20-1]
• Formula: C29H31N5O4

Application Notes

• Application Notes: ZM-447439 is a selective ATP-competitive inhibitor of Aurora kinase B1 (IC50 = 50 nM, Aur A IC50 = 1 µM, Aur C IC50 = 250 nM at physiological ATP concentrations2, Ref.1 lists Aur A IC50 = 110nM and Aur B IC50 = 113nM). It did not significantly inhibit a