95% by TLC [10% methanol in methylene chloride, Rf = 0.34] NMR conforms
Form:
Yellow solid
CAS Number:
[115104-28-4]
Formula:
C26H27ClN2O3S2
Application Notes:
Potent (EC50 = 1.3nM) and selective Leukotriene D4 antagonist(LTD4)1 displaying inverse agonist activity2, Blocks binding of LTD4 to human (Ki = 0.22 nM) and guinea pig (Ki = 2.1 nM) lung membranes. Selective for the CysLT1 receptor. Multidrug resistance
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