98% by TLC [5% methanol in methylene chloride, Rf= 0.27] NMR conforms
Form:
yellow solid (MP = 209-211C)
CAS Number:
[354812-17-2]
Formula:
C9H8N2OS2
Application Notes:
Reversible, competitive inhibitor of IKK2 (IC50 = 11.2 µM). Has not been demonstrated to inhibit other IKK isoforms, or other kinases. Displays dose-dependent inhibition of the transcription of NK-kappaB dependent genes in cell culture1.
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