98% by TLC [50% ethyl acetate in hexanes, Rf = 0.58] NMR Conforms
Form:
white solid (MP = 128-130C)
CAS Number:
[944261-79-4]
Formula:
C19H16ClNO4
Application Notes:
Potent, selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8. Nav1.8 is preferentially expressed in sensory neurons, and inhibition attenuates both inflammatory and neuropathic pain in a variety of animal models. IC50s for rat and
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