Ko-143, CAS [[461054-93-3]]

Product Overview

• Article Name: Ko-143, CAS [[461054-93-3]]
• Biozol Catalog Number: FBM-10-1074
• Supplier Catalog Number: 10-1074
• Alternative Catalog Number: FBM-10-1074-5MG,FBM-10-1074-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

BCRP inhibitor

Product Properties

• Molecular Weight: 470.59
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [461054-93-3]
• Formula: C26H36N3O5

Application Notes

• Application Notes: A potent and selective inhibitor of the breast cancer resistance protein multidrug transporter (BCRP/ABCG2)1. Reverses resistance of MTX and topotecan at 25 nM in human and mouse cell lines.1 Also inhibits ABCB1 and ABCC1 at concentrations >1 µM.2 Restor