Chemical Name: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
SIRT1 inhibitor
Molecular Weight:
248.71
Purity:
98% by TLC, NMR conforms
Form:
Light yellow solid
CAS Number:
[49843-98-3]
Formula:
C13H13ClN2O
Application Notes:
Selective SIRT1 inhibitor (IC50=98 nM). Does not inhibit other HDACs or SIRT family members. Increases p53 acetylation following DNA damage. Cell permeable.
10-1083
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