99% by TLC [5% methanol in methylene chloride, Rf = 0.76] NMR Conforms
Form:
Yellow solid (MP = 223-224C)
CAS Number:
[148741-30-4]
Formula:
C18H24N2OS
Application Notes:
Inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 µM). No inhibition of EGF, or PDGF receptor phosphorylation at typical working concentrations.
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