PIT-1, CAS [[53501-41-0]]
Catalog Number:
FBM-10-1192
Article Name: |
PIT-1, CAS [[53501-41-0]] |
Biozol Catalog Number: |
FBM-10-1192 |
Supplier Catalog Number: |
10-1192 |
Alternative Catalog Number: |
FBM-10-1192-10MG,FBM-10-1192-50MG |
Manufacturer: |
Focus Biomolecules |
Category: |
Biochemikalien |
Molecular Weight: |
351.76 |
Purity: |
98% by TLC, NMR (Conforms) |
Form: |
Grey solid |
CAS Number: |
[53501-41-0] |
Formula: |
C14H10ClN3O4S |
Application Notes: |
PH domain antagonist. Specifically blocks the binding of PIP3 to the Akt pleckstrin homology domain (IC50 = 31 µM). Suppresses PI3K-PDK1-Akt-dependent phosphorylation. Induces apoptosis in PTEN-deficient U87MG glioblastoma cells (IC50 = 37 µM)1. Inhibiti |