PIT-1, CAS [[53501-41-0]]

Catalog Number: FBM-10-1192
Article Name: PIT-1, CAS [[53501-41-0]]
Biozol Catalog Number: FBM-10-1192
Supplier Catalog Number: 10-1192
Alternative Catalog Number: FBM-10-1192-10MG,FBM-10-1192-50MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
PH domain antagonist
Molecular Weight: 351.76
Purity: 98% by TLC, NMR (Conforms)
Form: Grey solid
CAS Number: [53501-41-0]
Formula: C14H10ClN3O4S
Application Notes: PH domain antagonist. Specifically blocks the binding of PIP3 to the Akt pleckstrin homology domain (IC50 = 31 µM). Suppresses PI3K-PDK1-Akt-dependent phosphorylation. Induces apoptosis in PTEN-deficient U87MG glioblastoma cells (IC50 = 37 µM)1. Inhibiti