An IP3 receptor antagonist (IC50=42 µM).1 Inhibits store-operated Ca2+ channels at high concentrations (50 µM) but stimulates at low concs. (<10 µM).2 Modulates TRP channels, blocking TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8, TRPP2 and at h
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