CHIR-99021, CAS [[252917-06-9]]

Product Overview

• Article Name: CHIR-99021, CAS [[252917-06-9]]
• Biozol Catalog Number: FBM-10-1279
• Supplier Catalog Number: 10-1279
• Alternative Catalog Number: FBM-10-1279-5MG,FBM-10-1279-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

GSK3beta inhibitor

Product Properties

• Molecular Weight: 465.35
• Purity: 99% by TLC, NMR (conforms)
• Form: Tan solid
• CAS Number: [252917-06-9]
• Formula: C22H18Cl2N8

Application Notes

• Application Notes: Potent and selective inhibitor of glycogen synthase kinase-3beta (GSK3beta, IC50 = 5 nM) and GSK3alpha (IC50 = 10 nM)1. Induces osteoblastogenesis, increases mineralization and inhibits adipogenesis in ST2 cells2. Promotes replication and survival of pancreatic be