6-Thioguanine, CAS [[154-42-7]]

Product Overview

• Article Name: 6-Thioguanine, CAS [[154-42-7]]
• Biozol Catalog Number: FBM-10-1282
• Supplier Catalog Number: 10-1282
• Alternative Catalog Number: FBM-10-1282-100MG,FBM-10-1282-1G
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: 6-TG, NSC 752, NSC 76504

Product Description

Anticancer agent / downregulates DNMT1

Product Properties

• Molecular Weight: 167.19
• Purity: 96% by HPLC NMr (Conforms)
• Form: Pale yellow solid
• CAS Number: [154-42-7]
• Formula: C5H5N5S

Application Notes

• Application Notes: After incorporation into DNA, it disrupts cytosine methylation by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo.1 It reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasom