Potent, ATP-competitive inhibitor of Clk-family kinases (IC50s = 15, 20 and 200 nM for mClk4, 1 and 2 respectively and >10 µM for mClk3)1. Also inhibits DYRK1A/B (IC50s = 24 and 34 nM respectively)2. Suppresses serine/arginine-rich protein phosphorylatio
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