MLN4924, CAS [[905579-51-3]]

Product Overview

• Article Name: MLN4924, CAS [[905579-51-3]]
• Biozol Catalog Number: FBM-10-1311
• Supplier Catalog Number: 10-1311
• Alternative Catalog Number: FBM-10-1311-1MG,FBM-10-1311-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Pevonedistat

Product Description

Nedd8 activating enzyme inhibitor

Product Properties

• Molecular Weight: 443.53
• Purity: 98% by TLC, NMR conforms
• Form: White solid
• CAS Number: [905579-51-3]
• Formula: C21H25N5O4S

Application Notes

• Application Notes: MLN4924 is a potent and selective NEDD8-activating enzyme (NAE) inhibitor.1 It disrupts cullin-RING ligase-mediated protein turnover leading to apoptosis in human tumor cells. Suppresses the growth of human tumor xenografts in mice.2 Upregulates PD-L1 ex