Selective mitotic kinesin Eg5 inhibitor (IC50 = 1.3 µM) which acts in an ATP-noncompetitive manner1,2. It is at least 150-fold more selective for Eg5 than other members of the kinesin superfamily. K858 blocks centrosome separation, activates the spindle
* VAT and and shipping costs not included. Errors and price changes excepted