SMI-4a, CAS [[438190-29-5]]

Product Overview

• Article Name: SMI-4a, CAS [[438190-29-5]]
• Biozol Catalog Number: FBM-10-1359
• Supplier Catalog Number: 10-1359
• Alternative Catalog Number: FBM-10-1359-5MG,FBM-10-1359-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

PIM1 inhibitor

Product Properties

• Molecular Weight: 273.23
• Purity: 98% by TLC, NMR (conforms)
• Form: Tan solid
• CAS Number: [438190-29-5]
• Formula: C11H6F3NO2S

Application Notes

• Application Notes: A selective, ATP-competitive inhibitor of the Pim protein kinases (IC50 = 24 and 100 nM for Pim-1 and Pim-2 respectively). Selective over a panel of ~50 other kinases1. Induces cell cycle arrest in leukemia and prostate cancer cells2. Blocks the growth o