JQ1 (+/-), CAS [[1268524-69-1]]

Product Overview

• Article Name: JQ1 (+/-), CAS [[1268524-69-1]]
• Biozol Catalog Number: FBM-10-1361
• Supplier Catalog Number: 10-1361
• Alternative Catalog Number: FBM-10-1361-5MG,FBM-10-1361-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Bromodomain inhibitor

Product Properties

• Molecular Weight: 457.00
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [1268524-69-1]
• Formula: C23H25ClN4O2S

Application Notes

• Application Notes: JQ1 is a potent BET bromodomain inhibitor. IC50 = 17.7, 32.6, 76.9 and 12942 nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP respectively. Competitive binding by JQ1 displaces the BRD4 fusion oncoprotein from chromat