GSK-J1, CAS [[1373422-53-7]]

Product Overview

• Article Name: GSK-J1, CAS [[1373422-53-7]]
• Biozol Catalog Number: FBM-10-1393
• Supplier Catalog Number: 10-1393
• Alternative Catalog Number: FBM-10-1393-5MG,FBM-10-1393-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

JMJ H3K27 Demethylase inhibitor (Non-cell permeable)

Product Properties

• Molecular Weight: 389.46
• Purity: 99% by TLC, NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [1373422-53-7]
• Formula: C22H23N5O2

Application Notes

• Application Notes: Potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. Th