GSK-J4, CAS [[1373423-53-0]]

Product Overview

• Article Name: GSK-J4, CAS [[1373423-53-0]]
• Biozol Catalog Number: FBM-10-1394
• Supplier Catalog Number: 10-1394
• Alternative Catalog Number: FBM-10-1394-5MG,FBM-10-1394-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

JMJ H3K27 Demethylase inhibitor (Cell Permeable)

Product Properties

• Molecular Weight: 417.48
• Purity: 99% by TLC, NMR (Conforms)
• Form: Yellow waxy solid
• CAS Number: [1373423-53-0]
• Formula: C24H27N5O2

Application Notes

• Application Notes: Histone demethylase JMJD3/UTX inhibitor. Inhibits demethylation of histone H3K27. Reduces LPS-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 µM for the inhibition of TNFalpha release). Cell permeable, ethyl ester of GSK J1