PRT4165, CAS [[31083-55-3]]

Catalog Number: FBM-10-1478
Article Name: PRT4165, CAS [[31083-55-3]]
Biozol Catalog Number: FBM-10-1478
Supplier Catalog Number: 10-1478
Alternative Catalog Number: FBM-10-1478-10MG,FBM-10-1478-50MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
E3 ubiquitin ligase inhibitor
Molecular Weight: 235.24
Purity: 98% by TLC, NMR (Conforms)
Form: Yellow solid
CAS Number: [31083-55-3]
Formula: C15H9NO2
Application Notes: Inhibitor of Bmi1/Ring1A, subunits of the polycomb repressive complex 1 (PRC1). Inhibits self-ubiquitination (IC50 = 3.9 µM) but does not increase cellular levels of either subunit. Blocks Bmi1/Ring1A-mediated ubiquitination and drug-induced degradation