LY-364947, CAS [[396129-53-6]]

Product Overview

• Article Name: LY-364947, CAS [[396129-53-6]]
• Biozol Catalog Number: FBM-10-1492
• Supplier Catalog Number: 10-1492
• Alternative Catalog Number: FBM-10-1492-5MG,FBM-10-1492-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: HTS-466284

Product Description

ALK5 inhibitor

Product Properties

• Molecular Weight: 272.31
• Purity: 98% by TLC
• Form: Beige solid
• CAS Number: [396129-53-6]
• Formula: C17H12N4

Application Notes

• Application Notes: Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-beta RI, TGF-beta RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-beta as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-