LY364947, CAS [[396129-53-6]]

Catalog Number: FBM-10-1492
Article Name: LY364947, CAS [[396129-53-6]]
Biozol Catalog Number: FBM-10-1492
Supplier Catalog Number: 10-1492
Alternative Catalog Number: FBM-10-1492-5MG,FBM-10-1492-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: HTS-466284
ALK5 inhibitor
Molecular Weight: 272.31
Purity: 98% by TLC
Form: Beige solid
CAS Number: [396129-53-6]
Formula: C17H12N4
Application Notes: Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-beta RI, TGF-beta RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-beta as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-