HIF-2alpha-I2, CAS [[1422955-31-4]]

Product Overview

• Article Name: HIF-2alpha-I2, CAS [[1422955-31-4]]
• Biozol Catalog Number: FBM-10-1508
• Supplier Catalog Number: 10-1508
• Alternative Catalog Number: FBM-10-1508-5MG,FBM-10-1508-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: TC-S 7009

Product Description

HIF-2alpha antagonist

Product Properties

• Molecular Weight: 308.65
• Purity: 98% by TLC, NMR (Conforms)
• Form: Yellow solid
• CAS Number: [1422955-31-4]
• Formula: C12H6ClFN4O3

Application Notes

• Application Notes: Potent and selective HIF-2alpha inhibitor, Kd=81 nM.1 Binds to the HIF-2alpha PAS-B domain2 and interferes with Hif-2alpha / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2alpha displaying a >60-fold selectivity o