Tyrphostin a9, Malonoben, AG-17, SF 6847, RG-50872
PDGFR kinase inhibitor and Ox. phosphorylation inhibitor
Molecular Weight:
282.38
Purity:
99% by TLC, NMR (Conforms)
Form:
Orange solid
CAS Number:
[10537-47-0]
Formula:
C18H22N2O
Application Notes:
Inhibits PDGF receptor tyrosine kinase (IC50 = 1.2 µM)1 and is a potent (10 nM) inhibitor of oxidative phosphorylation2. Inhibits cell growth by disrupting mitochondria3. Perturbs the golgi complex and blocks proliferation of vascular smooth muscle cells
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