Dabrafenib, CAS [[1195765-45-7]]

Product Overview

• Article Name: Dabrafenib, CAS [[1195765-45-7]]
• Biozol Catalog Number: FBM-10-1569
• Supplier Catalog Number: 10-1569
• Alternative Catalog Number: FBM-10-1569-5MG,FBM-10-1569-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: GSK2118436

Product Description

B-Raf mutant inhibitor

Product Properties

• Molecular Weight: 519.56
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1195765-45-7]
• Formula: C23H20F3N5O2S

Application Notes

• Application Notes: Dabrafenib is a selective inhibitor of mutant B-RafV600E (IC50 = 0.8 nM), with 4- and 6-fold reduced potency against wild type B-Raf and c-Raf (IC50 = 3.2 and 5 nM, respectively).1 Has been in clinical trials in patients with B-RafV600E metastatic melano