4mu8C, CAS [[14003-96-4]]

Product Overview

• Article Name: 4mu8C, CAS [[14003-96-4]]
• Biozol Catalog Number: FBM-10-1579
• Supplier Catalog Number: 10-1579
• Alternative Catalog Number: FBM-10-1579-5MG,FBM-10-1579-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

IRE1 ribonuclease inhibitor

Product Properties

• Molecular Weight: 204.18
• Purity: 97% by TLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [14003-96-4]
• Formula: C11H8O4

Application Notes

• Application Notes: Selective inhibitor of IRE1alpha ribonuclease (RNase) activity (IC50 = 60 nM). Covalently binds to lysine 907 in the IRE1 endonuclease domain, blocking substrate access to the active site of IRE1alpha and inactivating both XBP1 splicing and IRE1alpha-mediated mRNA d