JQ1 (+), CAS [[1268524-70-4]]

Product Overview

• Article Name: JQ1 (+), CAS [[1268524-70-4]]
• Biozol Catalog Number: FBM-10-1584
• Supplier Catalog Number: 10-1584
• Alternative Catalog Number: FBM-10-1584-5MG,FBM-10-1584-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

BET Bromodomain inhibitor

Product Properties

• Molecular Weight: 456.99
• Purity: 98% by HPLC NMR conforms
• Form: White solid
• CAS Number: [1268524-70-4]
• Formula: C23H25ClN4O2S

Application Notes

• Application Notes: Potent BET bromodomain inhibitor and is the active isomer. IC50 = 17.7, 32.6, 76.9 and 12942 nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP respectively (data for + isomer).1 Competitive binding by JQ1 displaces the