CBR-5884, CAS [[681159-27-3]]

Product Overview

• Article Name: CBR-5884, CAS [[681159-27-3]]
• Biozol Catalog Number: FBM-10-1588
• Supplier Catalog Number: 10-1588
• Alternative Catalog Number: FBM-10-1588-5MG,FBM-10-1588-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

PHGDH / serine biosynthesis inhibitor

Product Properties

• Molecular Weight: 336.39
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [681159-27-3]
• Formula: C14H12N2O4S2

Application Notes

• Application Notes: Potent and selective inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), IC50=33 µM1. The action of PHGDH is the first committed step of serine biosynthesis2 and certain cancer cells overexpress PHGDH3. CBR-5884 inhibits serine biosynthesis in cells w