PBIT, CAS [[2514-30-9]]

Catalog Number: FBM-10-1595
Article Name: PBIT, CAS [[2514-30-9]]
Biozol Catalog Number: FBM-10-1595
Supplier Catalog Number: 10-1595
Alternative Catalog Number: FBM-10-1595-5MG,FBM-10-1595-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
JARID1 lysine demethylase inhibitor
Molecular Weight: 241.31
Purity: 98% by TLC, NMR (Conforms)
Form: Off-white solid
CAS Number: [2514-30-9]
Formula: C14H11NOS
Application Notes: The JARID1 (Jumonji AT-Rich Interactive Domain 1) family of lysine demethylases demethylates the trimethylated lysine 27 in histone H3 (H3K4me3). PBIT is a potent and selective inhibitor of JARID1 (IC50 = 3, 4.9 and 6 µM for JARID1B, 1A and 1C, respectiv