Mithramycin A, CAS [[18378-89-7]]

Product Overview

• Article Name: Mithramycin A, CAS [[18378-89-7]]
• Biozol Catalog Number: FBM-10-2085
• Supplier Catalog Number: 10-2085
• Alternative Catalog Number: FBM-10-2085-1MG,FBM-10-2085-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: A2371, Antibiotic LA 7017, Aureolic Acid, NSC 24559, PA 144, Plicamycin

Product Description

Transcription inhibitor

Product Properties

• Molecular Weight: 1085.15
• Purity: 98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [18378-89-7]
• Formula: C52H76O24

Application Notes

• Application Notes: Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL