Axitinib, CAS [[319460-85-0]]

Product Overview

• Article Name: Axitinib, CAS [[319460-85-0]]
• Biozol Catalog Number: FBM-10-2118
• Supplier Catalog Number: 10-2118
• Alternative Catalog Number: FBM-10-2118-10MG,FBM-10-2118-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

VEGFR kinase inhibitor

Product Properties

• Molecular Weight: 386.47
• Purity: 99% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [319460-85-0]
• Formula: C22H18N4OS

Application Notes

• Application Notes: Potent inhibitor of VEGFR-2, -3, and -1, IC50 = 0.2, 0.1-0.3, and 1.2 nM respectively1 displaying minimal activity against a panel of ~100 protein kinases. Inhibits angiogenesis and vascular permeability.2 Also inhibits BCR-ABL1 (T315I) with high potency