Bosutinib, CAS [[380843-75-4]]

Product Overview

• Article Name: Bosutinib, CAS [[380843-75-4]]
• Biozol Catalog Number: FBM-10-2122
• Supplier Catalog Number: 10-2122
• Alternative Catalog Number: FBM-10-2122-5MG,FBM-10-2122-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: SKI-606

Product Description

Dual Src/Abl kinase inhibitor

Product Properties

• Molecular Weight: 530.45
• Purity: >98% by HPLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [380843-75-4]
• Formula: C26H29Cl2N5O3

Application Notes

• Application Notes: An ATP-competitive dual Src/Abl kinase inhibitor (IC50 = 1 nM).1 It potently inhibits the apoptosis-linked STE20 kinases but does not inhibit Kit or PDGFR.2 Bosutinib was found to inhibit 16 of 18 imatinib-resistant mutant forms of Bcr-Abl expressed in m