Dovitinib, CAS [[405169-16-6]]
Catalog Number:
FBM-10-2129
Article Name: |
Dovitinib, CAS [[405169-16-6]] |
Biozol Catalog Number: |
FBM-10-2129 |
Supplier Catalog Number: |
10-2129 |
Alternative Catalog Number: |
FBM-10-2129-5MG,FBM-10-2129-25MG |
Manufacturer: |
Focus Biomolecules |
Category: |
Biochemikalien |
Alternative Names: |
TKI-258, CHIR258 |
Molecular Weight: |
392.43 |
Purity: |
99% by TLC, 99% by HPLC |
Form: |
Yellow-green solid |
CAS Number: |
[405169-16-6] |
Formula: |
C21H21FN6O |
Application Notes: |
Potent kinase inhibitor. Inhibits FLT3 (IC50 = 1 nM), c-KIT (IC50 = 2 nM), FGFR (IC50 = 8 nM), VEGFR1/2/3 (IC50 = 10 nM), PDGFRbeta (IC50 = 27 nM), and CSF-1R (IC50 = 36 nM).1 Active in cell culture and in whole animals. Selectively blocks the growth B9 cel |