MS-275, CAS [[209783-80-2]]

Product Overview

• Article Name: MS-275, CAS [[209783-80-2]]
• Biozol Catalog Number: FBM-10-2131
• Supplier Catalog Number: 10-2131
• Alternative Catalog Number: FBM-10-2131-5MG,FBM-10-2131-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Entinostat, SNDX-275

Product Description

HDAC inhibitor

Product Properties

• Molecular Weight: 376.42
• Purity: 98% by TLC, NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [209783-80-2]
• Formula: C21H20N4O3

Application Notes

• Application Notes: Potent HDAC inhibitor. Selective for HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 µM) and HDAC8 (IC50 > 100 µM).1 In vivo, MS-275 has been shown to inhibit tumor growth via induction of the tumor supressors p21WAF1/CIP1 and gelsolin2 and to block cell prol