H89 2HCl, CAS [[127243-85-0]]

Product Overview

• Article Name: H89 2HCl, CAS [[127243-85-0]]
• Biozol Catalog Number: FBM-10-2144
• Supplier Catalog Number: 10-2144
• Alternative Catalog Number: FBM-10-2144-5MG,FBM-10-2144-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

PKA inhibitor

Product Properties

• Molecular Weight: 519.28
• Purity: 98% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [127243-85-0]
• Formula: C20H20BrN3O2S2HCl

Application Notes

• Application Notes: H-89 is a commonly used inhibitor of protein kinase A (PKA IC50 = 140 nM). Inhibits a variety of other kinases including S6K1 (IC50 = 80 nM), MSK1 (120 nM), ROCK II (270 nM), PKBalpha (2.6 µM), PKD, PRK2, RSK1 and 2, SGK, AMPK, CHK1 and MAPKAP-K1b (2.8 µM).1