Pazopanib, CAS [[444731-52-6]]

Product Overview

• Article Name: Pazopanib, CAS [[444731-52-6]]
• Biozol Catalog Number: FBM-10-2158
• Supplier Catalog Number: 10-2158
• Alternative Catalog Number: FBM-10-2158-10MG,FBM-10-2158-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: GSK-VEG10003, GW786034B

Product Description

Multi-receptor tyrosine kinase inhibitor

Product Properties

• Molecular Weight: 437.52
• Purity: >98% by HPLC NMR (Conforms)
• Form: White to off-white solid
• CAS Number: [444731-52-6]
• Formula: C21H23N7O2S

Application Notes

• Application Notes: Inhibits multiple receptor tyrosine kinases including VEGFR1,2 and 3 (IC50s=10, 30, 47 nM respectively) and PDGFRalpha, beta and c-Kit (IC50s=71, 84, 74 nM respectively) and others such as FGFR.1 The drug targets both the tumor and endothelial cells in a mouse